Hypoxia Enhances Chondrogenesis and Prevents Terminal Differentiation through PI3K/Akt/FoxO Dependent Anti-Apoptotic Effect

Hypoxia, a common environmental condition, influences cell signals and functions. Here, we compared the effects of hypoxia (1% oxygen) and normoxia (air) on chondrogenic differentiation of human mesenchymal stem cells (MSCs). For in vitro chondrogenic differentiation, MSCs were concentrated to form...

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Detalles Bibliográficos
Autores principales: Lee, Hsieh-Hsing, Chang, Chia-Chi, Shieh, Ming-Jium, Wang, Jung-Pan, Chen, Yi-Te, Young, Tai-Horng, Hung, Shih-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775095/
https://www.ncbi.nlm.nih.gov/pubmed/24042188
http://dx.doi.org/10.1038/srep02683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775095/
https://www.ncbi.nlm.nih.gov/pubmed/24042188
http://dx.doi.org/10.1038/srep02683

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