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Live cell detection of chromosome 2 deletion and Sfpi1/PU1 loss in radiation-induced mouse acute myeloid leukaemia()

The CBA/H mouse model of radiation-induced acute myeloid leukaemia (rAML) has been studied for decades to bring to light the molecular mechanisms associated with multistage carcinogenesis. A specific interstitial deletion of chromosome 2 found in a high proportion of rAML is recognised as the initia...

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Detalles Bibliográficos
Autores principales: Olme, C.-H., Finnon, R., Brown, N., Kabacik, S., Bouffler, S.D., Badie, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775122/
https://www.ncbi.nlm.nih.gov/pubmed/23806234
http://dx.doi.org/10.1016/j.leukres.2013.05.019