Cargando…

Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus

Extrasynaptic γ-aminobutyric acid type A (GABA(A)) receptors that contain the δ subunit (δGABA(A) receptors) are expressed in several brain regions including the dentate gyrus (DG) and CA1 subfields of the hippocampus. Drugs that increase δGABA(A) receptor activity have been proposed as treatments f...

Descripción completa

Detalles Bibliográficos
Autores principales: Whissell, Paul D., Eng, Dave, Lecker, Irene, Martin, Loren J., Wang, Dian-Shi, Orser, Beverley A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775149/
https://www.ncbi.nlm.nih.gov/pubmed/24062648
http://dx.doi.org/10.3389/fncir.2013.00146