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Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus
Extrasynaptic γ-aminobutyric acid type A (GABA(A)) receptors that contain the δ subunit (δGABA(A) receptors) are expressed in several brain regions including the dentate gyrus (DG) and CA1 subfields of the hippocampus. Drugs that increase δGABA(A) receptor activity have been proposed as treatments f...
Autores principales: | Whissell, Paul D., Eng, Dave, Lecker, Irene, Martin, Loren J., Wang, Dian-Shi, Orser, Beverley A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775149/ https://www.ncbi.nlm.nih.gov/pubmed/24062648 http://dx.doi.org/10.3389/fncir.2013.00146 |
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