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Quantitative trait locus linkage analysis in a large Amish pedigree identifies novel candidate loci for erythrocyte traits

We characterized a large Amish pedigree and, in 384 pedigree members, analyzed the genetic variance components with covariate screen as well as genome-wide quantitative trait locus (QTL) linkage analysis of red blood cell count (RBC), hemoglobin (HB), hematocrit (HCT), mean corpuscular volume (MCV),...

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Detalles Bibliográficos
Autores principales: Hinckley, Jesse D, Abbott, Diana, Burns, Trudy L, Heiman, Meadow, Shapiro, Amy D, Wang, Kai, Di Paola, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775389/
https://www.ncbi.nlm.nih.gov/pubmed/24058921
http://dx.doi.org/10.1002/mgg3.16