Cargando…

Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer

Alternative splicing is a fundamental step in regulation of gene expression of many tumor suppressors and oncogenes in cancer. Signalling through the Ras-MAPK and PI3K-mTOR pathways is misregulated and hyperactivated in most types of cancer. However, the regulation of the Ras-MAPK and PI3K-mTOR sign...

Descripción completa

Detalles Bibliográficos
Autores principales: Siegfried, Zahava, Bonomi, Serena, Ghigna, Claudia, Karni, Rotem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775402/
https://www.ncbi.nlm.nih.gov/pubmed/24078813
http://dx.doi.org/10.1155/2013/568931