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Regulation of the Ras-MAPK and PI3K-mTOR Signalling Pathways by Alternative Splicing in Cancer

Alternative splicing is a fundamental step in regulation of gene expression of many tumor suppressors and oncogenes in cancer. Signalling through the Ras-MAPK and PI3K-mTOR pathways is misregulated and hyperactivated in most types of cancer. However, the regulation of the Ras-MAPK and PI3K-mTOR sign...

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Detalles Bibliográficos
Autores principales:	Siegfried, Zahava, Bonomi, Serena, Ghigna, Claudia, Karni, Rotem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775402/ https://www.ncbi.nlm.nih.gov/pubmed/24078813 http://dx.doi.org/10.1155/2013/568931

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