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Genome-wide shRNA screening to identify factors mediating Gata6 repression in mouse embryonic stem cells
The use of whole-genome pooled shRNA libraries in loss-of-function screening in tissue culture models provides an effective means to identify novel factors acting in pathways of interest. Embryonic stem cells (ESCs) offer a unique opportunity to study processes involved in stem cell pluripotency and...
Autores principales: | Cooper, Sarah, Brockdorff, Neil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775421/ https://www.ncbi.nlm.nih.gov/pubmed/24046324 http://dx.doi.org/10.1242/dev.094615 |
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