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Lesion-Induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus

Astrocytes express the sodium-dependent glutamate transporters GLAST and GLT-1, which are critical to maintain low extracellular glutamate concentrations. Here, we analyzed changes in their expression and function following a mechanical lesion in the CA1 area of organotypic hippocampal slices. 6-7 d...

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Detalles Bibliográficos
Autores principales: Schreiner, Alexandra E., Berlinger, Eric, Langer, Julia, Kafitz, Karl W., Rose, Christine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775433/
https://www.ncbi.nlm.nih.gov/pubmed/24078881
http://dx.doi.org/10.1155/2013/893605