SOCS3 Expression Correlates with Severity of Inflammation, Expression of Proinflammatory Cytokines, and Activation of STAT3 and p38 MAPK in LPS-Induced Inflammation In Vivo

SOCS3 is an inducible endogenous negative regulator of JAK/STAT pathway, which is relevant in inflammatory conditions. We used a model of LPS-induced periodontal disease in rats to correlate SOCS3 expression with the inflammatory status. In vitro we used a murine macrophage cell line to assess the p...

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Detalles Bibliográficos
Autores principales: Chaves de Souza, João Antônio, Nogueira, Andressa Vilas Boas, Chaves de Souza, Pedro Paulo, Kim, Yeon Jung, Silva Lobo, Caroline, Pimentel Lopes de Oliveira, Guilherme José, Cirelli, Joni Augusto, Garlet, Gustavo Pompermaier, Rossa, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775441/
https://www.ncbi.nlm.nih.gov/pubmed/24078776
http://dx.doi.org/10.1155/2013/650812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775441/
https://www.ncbi.nlm.nih.gov/pubmed/24078776
http://dx.doi.org/10.1155/2013/650812

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