Cargando…

Induction of retinol-binding protein 4 and placenta-specific 8 expression in human prostate cancer cells remaining in bone following osteolytic tumor growth inhibition by osteoprotegerin

New drugs that inhibit the osteoprotegerin (OPG)/receptor activator of NF-κB ligand (RANKL)/RANK pathway have demonstrated efficacy for the treatment of bone metastasis. Toxicities induced by these drugs, however, including osteonecrosis of the jaw and hypocalcemia, may adversely affect therapy. The...

Descripción completa

Detalles Bibliográficos
Autores principales: UEHARA, HISANORI, TAKAHASHI, TETSUYUKI, IZUMI, KEISUKE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775580/
https://www.ncbi.nlm.nih.gov/pubmed/23708710
http://dx.doi.org/10.3892/ijo.2013.1954