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DPP6 regulation of dendritic morphogenesis impacts hippocampal synaptic development

Dipeptidyl-peptidase 6 (DPP6) is an auxiliary subunit of Kv4-mediated A-type K(+) channels that, in addition to enhancing channel surface expression, potently accelerates their kinetics. The DPP6 gene has been associated with a number of human CNS disorders including ASDs and schizophrenia. Here we...

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Detalles Bibliográficos
Autores principales: Lin, Lin, Sun, Wei, Throesch, Ben, Kung, Faith, Decoster, Jameice T, Berner, Cory J, Cheney, Richard E., Rudy, Bernardo, Hoffman, Dax A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775611/
https://www.ncbi.nlm.nih.gov/pubmed/23912628
http://dx.doi.org/10.1038/ncomms3270