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Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines

Objectives. Marijuana is the most commonly used illicit drug during pregnancy. Due to high lipophilicity, cannabinoids can easily penetrate physiological barriers like the human placenta and jeopardize the developing fetus. We evaluated the impact of cannabidiol (CBD), a major non-psychoactive canna...

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Detalles Bibliográficos
Autores principales: Feinshtein, Valeria, Erez, Offer, Ben-Zvi, Zvi, Erez, Noam, Eshkoli, Tamar, Sheizaf, Boaz, Sheiner, Eyal, Huleihel, Mahmud, Holcberg, Gershon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775628/
https://www.ncbi.nlm.nih.gov/pubmed/24058883
http://dx.doi.org/10.7717/peerj.153