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BD-Func: a streamlined algorithm for predicting activation and inhibition of pathways

BD-Func (BiDirectional FUNCtional enrichment) is an algorithm that calculates functional enrichment by comparing lists of pre-defined genes that are known to be activated versus inhibited in a pathway or by a regulatory molecule. This paper shows that BD-Func can correctly predict cell line alternat...

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Detalles Bibliográficos
Autores principales: Warden, Charles D., Kanaya, Noriko, Chen, Shiuan, Yuan, Yate-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775632/
https://www.ncbi.nlm.nih.gov/pubmed/24058887
http://dx.doi.org/10.7717/peerj.159