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Emerging targets in pancreatic cancer: epithelial–mesenchymal transition and cancer stem cells

Pancreatic ductal adenocarcinoma is one of the most aggressive solid malignancies and is characterized by poor response to current therapy and a dismal survival rate. Recent insights regarding the role of cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT) in tumorigenesis have brou...

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Detalles Bibliográficos
Autores principales: Castellanos, Jason A, Merchant, Nipun B, Nagathihalli, Nagaraj S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775701/
https://www.ncbi.nlm.nih.gov/pubmed/24049451
http://dx.doi.org/10.2147/OTT.S34670