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Generalization and Dilution of Association Results from European GWAS in Populations of Non-European Ancestry: The PAGE Study

The vast majority of genome-wide association study (GWAS) findings reported to date are from populations with European Ancestry (EA), and it is not yet clear how broadly the genetic associations described will generalize to populations of diverse ancestry. The Population Architecture Using Genomics...

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Detalles Bibliográficos
Autores principales: Carlson, Christopher S., Matise, Tara C., North, Kari E., Haiman, Christopher A., Fesinmeyer, Megan D., Buyske, Steven, Schumacher, Fredrick R., Peters, Ulrike, Franceschini, Nora, Ritchie, Marylyn D., Duggan, David J., Spencer, Kylee L., Dumitrescu, Logan, Eaton, Charles B., Thomas, Fridtjof, Young, Alicia, Carty, Cara, Heiss, Gerardo, Le Marchand, Loic, Crawford, Dana C., Hindorff, Lucia A., Kooperberg, Charles L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775722/
https://www.ncbi.nlm.nih.gov/pubmed/24068893
http://dx.doi.org/10.1371/journal.pbio.1001661