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A Cullin1-Based SCF E3 Ubiquitin Ligase Targets the InR/PI3K/TOR Pathway to Regulate Neuronal Pruning

Pruning that selectively eliminates unnecessary axons/dendrites is crucial for sculpting the nervous system during development. During Drosophila metamorphosis, dendrite arborization neurons, ddaCs, selectively prune their larval dendrites in response to the steroid hormone ecdysone, whereas mushroo...

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Detalles Bibliográficos
Autores principales: Wong, Jack Jing Lin, Li, Song, Lim, Edwin Kok Hao, Wang, Yan, Wang, Cheng, Zhang, Heng, Kirilly, Daniel, Wu, Chunlai, Liou, Yih-Cherng, Wang, Hongyan, Yu, Fengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775723/
https://www.ncbi.nlm.nih.gov/pubmed/24068890
http://dx.doi.org/10.1371/journal.pbio.1001657