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Mitochondrial Inverted Repeats Strongly Correlate with Lifespan: mtDNA Inversions and Aging

Mitochondrial defects are implicated in aging and in a multitude of age-related diseases, such as cancer, heart failure, Parkinson’s disease, and Huntington’s disease. However, it is still unclear how mitochondrial defects arise under normal physiological conditions. Mitochondrial DNA (mtDNA) deleti...

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Detalles Bibliográficos
Autores principales: Yang, Jiang-Nan, Seluanov, Andrei, Gorbunova, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775743/
https://www.ncbi.nlm.nih.gov/pubmed/24069185
http://dx.doi.org/10.1371/journal.pone.0073318