Cargando…

Area-Specific Alterations of Synaptic Plasticity in the 5XFAD Mouse Model of Alzheimer’s Disease: Dissociation between Somatosensory Cortex and Hippocampus

Transgenic mouse models of Alzheimer’s disease (AD) that overproduce the amyloid beta peptide (Aβ) have highlighted impairments of hippocampal long-term synaptic plasticity associated with the progression of the disease. Here we examined whether the characteristics of one of the hallmarks of AD, i.e...

Descripción completa

Detalles Bibliográficos
Autores principales: Crouzin, Nadine, Baranger, Kevin, Cavalier, Mélanie, Marchalant, Yannick, Cohen-Solal, Catherine, Roman, François S., Khrestchatisky, Michel, Rivera, Santiago, Féron, François, Vignes, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775744/
https://www.ncbi.nlm.nih.gov/pubmed/24069328
http://dx.doi.org/10.1371/journal.pone.0074667