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The Ral Exchange Factor Rgl2 Promotes Cardiomyocyte Survival and Inhibits Cardiac Fibrosis

Cardiomyocytes compensate to acute cardiac stress by increasing in size and contractile function. However, prolonged stress leads to a decompensated response characterized by cardiomyocyte death, tissue fibrosis and loss of cardiac function. Identifying approaches to inhibit this transition to a dec...

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Detalles Bibliográficos
Autores principales: Scotland, Rebecca L., Allen, Leah, Hennings, Leah J., Post, Ginell R., Post, Steven R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775766/
https://www.ncbi.nlm.nih.gov/pubmed/24069211
http://dx.doi.org/10.1371/journal.pone.0073599