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The Ral Exchange Factor Rgl2 Promotes Cardiomyocyte Survival and Inhibits Cardiac Fibrosis
Cardiomyocytes compensate to acute cardiac stress by increasing in size and contractile function. However, prolonged stress leads to a decompensated response characterized by cardiomyocyte death, tissue fibrosis and loss of cardiac function. Identifying approaches to inhibit this transition to a dec...
Autores principales: | Scotland, Rebecca L., Allen, Leah, Hennings, Leah J., Post, Ginell R., Post, Steven R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775766/ https://www.ncbi.nlm.nih.gov/pubmed/24069211 http://dx.doi.org/10.1371/journal.pone.0073599 |
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