Lack of Endogenous IL-10 Enhances Production of Proinflammatory Cytokines and Leads to Brucella abortus Clearance in Mice

IL-10 is a cytokine that regulates the balance between pathogen clearance and immunopathology. Brucella abortus is an intracellular bacterium that causes chronic disease in humans and domestic animals. Here we evaluated the contribution of IL-10 in host immune response and pathology during B. abortu...

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Detalles Bibliográficos
Autores principales: Corsetti, Patrícia P., de Almeida, Leonardo A., Carvalho, Natália B., Azevedo, Vasco, Silva, Teane M. A., Teixeira, Henrique C., Faria, Ana C., Oliveira, Sergio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775771/
https://www.ncbi.nlm.nih.gov/pubmed/24069337
http://dx.doi.org/10.1371/journal.pone.0074729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775771/
https://www.ncbi.nlm.nih.gov/pubmed/24069337
http://dx.doi.org/10.1371/journal.pone.0074729

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