Cancer Stemness in Apc- vs. Apc/KRAS-Driven Intestinal Tumorigenesis

Constitutive activation of the Wnt pathway leads to adenoma formation, an obligatory step towards intestinal cancer. In view of the established role of Wnt in regulating stemness, we attempted the isolation of cancer stem cells (CSCs) from Apc- and Apc/KRAS-mutant intestinal tumours. Whereas CSCs ar...

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Detalles Bibliográficos
Autores principales: Ghazvini, Mehrnaz, Sonneveld, Petra, Kremer, Andreas, Franken, Patrick, Sacchetti, Andrea, Atlasi, Yaser, Roth, Sabrina, Joosten, Rosalie, Smits, Ron, Fodde, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775784/
https://www.ncbi.nlm.nih.gov/pubmed/24069241
http://dx.doi.org/10.1371/journal.pone.0073872

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775784/
https://www.ncbi.nlm.nih.gov/pubmed/24069241
http://dx.doi.org/10.1371/journal.pone.0073872

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