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Association between DNA Methyltransferases 3B Gene Polymorphisms and the Susceptibility to Acute Myeloid Leukemia in Chinese Han Population
DNMT3B plays a crucial role in the generation of aberrant methylation during carcinogenesis. Polymorphisms in the DNMT3B gene may influence the DNA methylation enzymatic activity of DNMT3B, thereby modulating the susceptibility to AML. Thus, we investigated the association between SNPs in the DNMT3B...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775800/ https://www.ncbi.nlm.nih.gov/pubmed/24069326 http://dx.doi.org/10.1371/journal.pone.0074626 |