LIA5 Is Required for Nuclear Reorganization and Programmed DNA Rearrangements Occurring during Tetrahymena Macronuclear Differentiation

During macronuclear differentiation of the ciliate Tetrahymena thermophila, genome-wide DNA rearrangements eliminate nearly 50 Mbp of germline derived DNA, creating a streamlined somatic genome. The transposon-like and other repetitive sequences to be eliminated are identified using a piRNA pathway...

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Detalles Bibliográficos
Autores principales: Shieh, Annie Wan Yi, Chalker, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775806/
https://www.ncbi.nlm.nih.gov/pubmed/24069402
http://dx.doi.org/10.1371/journal.pone.0075337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775806/
https://www.ncbi.nlm.nih.gov/pubmed/24069402
http://dx.doi.org/10.1371/journal.pone.0075337

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