The Terminator mouse is a diphtheria toxin receptor knockin mouse strain for rapid and efficient enrichment of desired cell lineages

Biomedical research often requires primary cultures of specific cell types, which are challenging to obtain at high purity in a reproducible fashion. Here we engineered the murine Rosa26 locus by introducing the diphtheria toxin receptor flanked by loxP sites. The resultant strain was nicknamed the...

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Detalles Bibliográficos
Autores principales: Guo, Jian-Kan, Shi, Hongmei, Koraishy, Farrukh, Marlier, Arnaud, Ding, Zhaowei, Shan, Alan, Cantley, Lloyd G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775868/
https://www.ncbi.nlm.nih.gov/pubmed/23739236
http://dx.doi.org/10.1038/ki.2013.202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775868/
https://www.ncbi.nlm.nih.gov/pubmed/23739236
http://dx.doi.org/10.1038/ki.2013.202

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