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Generation of Embryonic Stem Cells and Mice for Duchenne Research

Duchenne muscular dystrophy (DMD) is a muscle-wasting disease in which muscle is continuously damaged, resulting in loss of muscle tissue and function. Antisense-mediated exon skipping is a promising therapeutic approach for DMD. This method uses sequence specific antisense oligonucleotides (AONs) t...

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Detalles Bibliográficos
Autores principales: Veltrop, Marcel, van der Kaa, Jos, Claassens, Jill, van Vliet, Laura, Verbeek, Sjef, Aartsma-Rus, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775890/
https://www.ncbi.nlm.nih.gov/pubmed/24057032
http://dx.doi.org/10.1371/currents.md.cbf1d33001de80923ce674302cad7925