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The Functional Significance of Synaptotagmin Diversity in Neuroendocrine Secretion
Synaptotagmins (syts) are abundant, evolutionarily conserved integral membrane proteins that play essential roles in regulated exocytosis in nervous and endocrine systems. There are at least 17 syt isoforms in mammals, all with tandem C-terminal C2 domains with highly variable capacities for Ca(2+)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776153/ https://www.ncbi.nlm.nih.gov/pubmed/24065953 http://dx.doi.org/10.3389/fendo.2013.00124 |