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The Functional Significance of Synaptotagmin Diversity in Neuroendocrine Secretion

Synaptotagmins (syts) are abundant, evolutionarily conserved integral membrane proteins that play essential roles in regulated exocytosis in nervous and endocrine systems. There are at least 17 syt isoforms in mammals, all with tandem C-terminal C2 domains with highly variable capacities for Ca(2+)...

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Detalles Bibliográficos
Autores principales: Moghadam, Paanteha K., Jackson, Meyer B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776153/
https://www.ncbi.nlm.nih.gov/pubmed/24065953
http://dx.doi.org/10.3389/fendo.2013.00124