A novel ropivacaine-loaded in situ forming implant prolongs the effect of local analgesia in rats

INTRODUCTION: Prolonged postoperative analgesia cannot be achieved by a single injection of local anesthetic solution. The objective of this study was to optimize the formulation of a ropivacaine hydrochloride (Ropi-HCl) loaded in situ forming implant (ISI) by addition of different co-solvents, and...

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Detalles Bibliográficos
Autores principales: Lu, Lei, Zhang, Wei, Wu, Xin, Wang, Xiaoyu, Zhang, Min, Zhu, Quangang, Ding, Xueying, Xu, Zhiyun, Gao, Shen, Gao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2012
Materias:
Experimental Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776163/
https://www.ncbi.nlm.nih.gov/pubmed/24049519
http://dx.doi.org/10.5114/aoms.2012.30829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776163/
https://www.ncbi.nlm.nih.gov/pubmed/24049519
http://dx.doi.org/10.5114/aoms.2012.30829

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