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A novel ropivacaine-loaded in situ forming implant prolongs the effect of local analgesia in rats

INTRODUCTION: Prolonged postoperative analgesia cannot be achieved by a single injection of local anesthetic solution. The objective of this study was to optimize the formulation of a ropivacaine hydrochloride (Ropi-HCl) loaded in situ forming implant (ISI) by addition of different co-solvents, and...

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Detalles Bibliográficos
Autores principales:	Lu, Lei, Zhang, Wei, Wu, Xin, Wang, Xiaoyu, Zhang, Min, Zhu, Quangang, Ding, Xueying, Xu, Zhiyun, Gao, Shen, Gao, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2012
Materias:	Experimental Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776163/ https://www.ncbi.nlm.nih.gov/pubmed/24049519 http://dx.doi.org/10.5114/aoms.2012.30829

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