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Nephrons require Rho-kinase for proximal-distal polarity development

Epithelial tubules must have the right length and pattern for proper function. In the nephron, planar cell polarity controls elongation along the proximal-distal axis. As the tubule lengthens, specialized segments (proximal, distal etc.) begin to differentiate along it. Other epithelia need Rho-kina...

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Detalles Bibliográficos
Autores principales: Lindström, Nils O., Hohenstein, Peter, Davies, Jamie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776198/
https://www.ncbi.nlm.nih.gov/pubmed/24045698
http://dx.doi.org/10.1038/srep02692