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Nephrons require Rho-kinase for proximal-distal polarity development
Epithelial tubules must have the right length and pattern for proper function. In the nephron, planar cell polarity controls elongation along the proximal-distal axis. As the tubule lengthens, specialized segments (proximal, distal etc.) begin to differentiate along it. Other epithelia need Rho-kina...
Autores principales: | Lindström, Nils O., Hohenstein, Peter, Davies, Jamie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776198/ https://www.ncbi.nlm.nih.gov/pubmed/24045698 http://dx.doi.org/10.1038/srep02692 |
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