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Direct detection of alpha synuclein oligomers in vivo

BACKGROUND: Rat models of Parkinson’s disease are widely used to elucidate the mechanisms underlying disease etiology or to investigate therapeutic approaches. Models were developed using toxins such as MPTP or 6-OHDA to specifically target dopaminergic neurons resulting in acute neuronal loss in th...

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Detalles Bibliográficos
Autores principales: Dimant, Hemi, Kalia, Suneil K, Kalia, Lorraine V, Zhu, Liya N, Kibuuka, Laura, Ebrahimi-Fakhari, Darius, McFarland, Nikolaus R, Fan, Zhanyun, Hyman, Bradley T, McLean, Pamela J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776213/
https://www.ncbi.nlm.nih.gov/pubmed/24252244
http://dx.doi.org/10.1186/2051-5960-1-6