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Compartmentalized Ras signaling differentially contributes to phenotypic outputs()

Ras isoforms are membrane bound proteins that differentially localize to the plasma membrane and subcellular compartments within the cell. Whilst the cell surface is the main site for Ras activity the extent to which intracellular pools contribute to Ras function is debated. We have generated Ras ch...

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Detalles Bibliográficos
Autores principales: Aran, Veronica, Prior, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776226/
https://www.ncbi.nlm.nih.gov/pubmed/23707528
http://dx.doi.org/10.1016/j.cellsig.2013.05.004