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Sensitive detection of BRAF V600E mutation by Amplification Refractory Mutation System (ARMS)-PCR

BACKGROUND: BRAF mutations occur in approximately 8% of all human cancers and approach 50% in melanoma and papillary carcinoma of thyroid. These mutations provide potentially valuable diagnostic, prognostic and treatment response prediction markers. A sensitive, specific, low-cost assay to detect th...

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Detalles Bibliográficos
Autores principales: Huang, Tiangui, Zhuge, Jian, Zhang, Wenyong W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776245/
https://www.ncbi.nlm.nih.gov/pubmed/24252159
http://dx.doi.org/10.1186/2050-7771-1-3