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Sensitive detection of BRAF V600E mutation by Amplification Refractory Mutation System (ARMS)-PCR
BACKGROUND: BRAF mutations occur in approximately 8% of all human cancers and approach 50% in melanoma and papillary carcinoma of thyroid. These mutations provide potentially valuable diagnostic, prognostic and treatment response prediction markers. A sensitive, specific, low-cost assay to detect th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776245/ https://www.ncbi.nlm.nih.gov/pubmed/24252159 http://dx.doi.org/10.1186/2050-7771-1-3 |