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Regulatory Interactions between Androgens, Hoxb5, and TGFβ Signaling in Murine Lung Development

Androgens enhance airway branching but delay alveolar maturation contributing to increased respiratory morbidity in prematurely born male infants. Hoxb5 protein positively regulates airway branching in developing lung. In other organs, androgen regulation intersects with Hox proteins and TGFβ-SMAD s...

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Detalles Bibliográficos
Autores principales: Volpe, MaryAnn V., Ramadurai, Sujatha M., Mujahid, Sana, Vong, Thanhxuan, Brandao, Marcia, Wang, Karen T., Pham, Lucia D., Nielsen, Heber C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776362/
https://www.ncbi.nlm.nih.gov/pubmed/24078914
http://dx.doi.org/10.1155/2013/320249