A Possible Role of HMGB1 in DNA Demethylation in CD4(+) T Cells from Patients with Systemic Lupus Erythematosus

The aberrant activity of CD4(+) T cells in patients with systemic lupus erythematosus (SLE) is associated with DNA hypomethylation of the regulatory regions in CD11a and CD70 genes. Our previous studies demonstrated that Gadd45a contributes to the development of SLE by promoting DNA demethylation in...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yaping, Huang, Chenghui, Zhao, Ming, Liang, Gongping, Xiao, Rong, Yung, Susan, Chan, Tak Mao, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776363/
https://www.ncbi.nlm.nih.gov/pubmed/24082908
http://dx.doi.org/10.1155/2013/206298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776363/
https://www.ncbi.nlm.nih.gov/pubmed/24082908
http://dx.doi.org/10.1155/2013/206298

Ejemplares similares