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Oxaliplatin induces different cellular and molecular chemoresistance patterns in colorectal cancer cell lines of identical origins
BACKGROUND: Cancer cells frequently adopt cellular and molecular alterations and acquire resistance to cytostatic drugs. Chemotherapy with oxaliplatin is among the leading treatments for colorectal cancer with a response rate of 50%, inducing intrastrand cross-links on the DNA. Despite of this drug’...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776436/ https://www.ncbi.nlm.nih.gov/pubmed/23865481 http://dx.doi.org/10.1186/1471-2164-14-480 |