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Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not ‘Diffusion-Limited’

[Image: see text] Coupled folding and binding of intrinsically disordered proteins (IDPs) is prevalent in biology. As the first step toward understanding the mechanism of binding, it is important to know if a reaction is ‘diffusion-limited’ as, if this speed limit is reached, the association must pr...

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Detalles Bibliográficos
Autores principales: Rogers, Joseph M., Steward, Annette, Clarke, Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776562/
https://www.ncbi.nlm.nih.gov/pubmed/23301700
http://dx.doi.org/10.1021/ja309527h