Alterations of Copy Number of Methylation Pattern in Mismatch Repair Genes by Methylation Specific-Multiplex Ligation-Dependent Probe Amplification in Cases of Colon Cancer

Genetic alterations and changes in genomic DNA cytosine methylation patterns are associated with all types of cancer and are caused by germline mutations in DNA mismatch repair (MMR) genes, predominantly MLH1 (MutL homolog 1, 19 exons) and MSH2 (MutS homolog 2, 16 exons). Genomic DNA was extracted f...

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Detalles Bibliográficos
Autores principales: Onrat, ST, Çeken, I, Ellidokuz, E, Kupelioğlu, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Macedonian Science of Sciences and Arts 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776700/
https://www.ncbi.nlm.nih.gov/pubmed/24052709
http://dx.doi.org/10.2478/v10034-011-0044-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776700/
https://www.ncbi.nlm.nih.gov/pubmed/24052709
http://dx.doi.org/10.2478/v10034-011-0044-x

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