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Ultrasound-targeted microbubble destruction enhances gene transduction of adeno-associated virus in a less-permissive cell type, NIH/3T3

Adeno-associated virus (AAV) is a common vector utilized in gene therapy. The NIH/3T3 cell line, which is a potential induced pluripotent stem (iPS) cell type, was identified to be a less-permissive cell type to AAV due to its defective endosomal processing. Ultrasound-targeted microbubble destructi...

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Detalles Bibliográficos
Autores principales: JIN, LIFANG, LI, FAN, WANG, HUIPING, LI, YUNHUA, WEI, FANG, DU, LIANFANG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776706/
https://www.ncbi.nlm.nih.gov/pubmed/23817930
http://dx.doi.org/10.3892/mmr.2013.1560