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Sphingosine kinase-1 mediates endotoxemia-induced hyperinflammation in aged animals

Sepsis is a serious issue in the geriatric population due to its association with high mortality rates in the elderly. The increase in mortality in the elderly correlates with inflammation. We have previously demonstrated that the inflammatory response is exacerbated in a rodent endotoxemia model of...

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Detalles Bibliográficos
Autores principales: LUFRANO, MARIA, JACOB, ASHA, ZHOU, MIAN, WANG, PING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776707/
https://www.ncbi.nlm.nih.gov/pubmed/23817990
http://dx.doi.org/10.3892/mmr.2013.1562