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HIF-1α knockdown by miRNA decreases survivin expression and inhibits A549 cell growth in vitro and in vivo
The present study examined the downregulation of survivin expression by hypoxia-inducible factor-1α (HIF-1α) miRNA and its effect in the inhibition of A549 cell growth in vitro and in vivo. Survivin expression, apoptosis, proliferation and migration under normoxic and hypoxic conditions were assesse...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776716/ https://www.ncbi.nlm.nih.gov/pubmed/23732337 http://dx.doi.org/10.3892/ijmm.2013.1405 |