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HIF-1α knockdown by miRNA decreases survivin expression and inhibits A549 cell growth in vitro and in vivo

The present study examined the downregulation of survivin expression by hypoxia-inducible factor-1α (HIF-1α) miRNA and its effect in the inhibition of A549 cell growth in vitro and in vivo. Survivin expression, apoptosis, proliferation and migration under normoxic and hypoxic conditions were assesse...

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Detalles Bibliográficos
Autores principales:	LI, WEI, CHEN, YU-QING, SHEN, YUAN-BING, SHU, HONG-MEI, WANG, XIAO-JING, ZHAO, CHENG-LING, CHEN, CHANG-JIE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776716/ https://www.ncbi.nlm.nih.gov/pubmed/23732337 http://dx.doi.org/10.3892/ijmm.2013.1405

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