Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells

It has been postulated that the most primitive population of stem cells, Oct4(+)Sca-1(+)Lin(−)CD45(−) very small embryonic-like stem cells (VSELs), differentiate into tissue-committed stem cells in adult mice. However, Oct4(+) VSELs remain quiescent in adult tissues and do not form teratomas. In thi...

Descripción completa

Detalles Bibliográficos
Autores principales: MIERZEJEWSKA, KATARZYNA, HEO, JINBEOM, KANG, JEONG WOOK, KANG, HYUNSOOK, RATAJCZAK, JANINA, RATAJCZAK, MARIUSZ Z., KUCIA, MAGDA, SHIN, DONG-MYUNG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776718/
https://www.ncbi.nlm.nih.gov/pubmed/23708325
http://dx.doi.org/10.3892/ijmm.2013.1389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776718/
https://www.ncbi.nlm.nih.gov/pubmed/23708325
http://dx.doi.org/10.3892/ijmm.2013.1389

Ejemplares similares