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Genome-wide analysis of murine bone marrow-derived very small embryonic-like stem cells reveals that mitogenic growth factor signaling pathways play a crucial role in the quiescence and ageing of these cells

It has been postulated that the most primitive population of stem cells, Oct4(+)Sca-1(+)Lin(−)CD45(−) very small embryonic-like stem cells (VSELs), differentiate into tissue-committed stem cells in adult mice. However, Oct4(+) VSELs remain quiescent in adult tissues and do not form teratomas. In thi...

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Detalles Bibliográficos
Autores principales:	MIERZEJEWSKA, KATARZYNA, HEO, JINBEOM, KANG, JEONG WOOK, KANG, HYUNSOOK, RATAJCZAK, JANINA, RATAJCZAK, MARIUSZ Z., KUCIA, MAGDA, SHIN, DONG-MYUNG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776718/ https://www.ncbi.nlm.nih.gov/pubmed/23708325 http://dx.doi.org/10.3892/ijmm.2013.1389

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