Enhanced Cardiac Function in Gravin Mutant Mice Involves Alterations in the β-Adrenergic Receptor Signaling Cascade

Gravin, an A-kinase anchoring protein, targets protein kinase A (PKA), protein kinase C (PKC), calcineurin and other signaling molecules to the beta2-adrenergic receptor (β(2)-AR). Gravin mediates desensitization/resensitization of the receptor by facilitating its phosphorylation by PKA and PKC. The...

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Detalles Bibliográficos
Autores principales: Guillory, Ashley N., Yin, Xing, Wijaya, Cori S., Diaz Diaz, Andrea C., Rababa’h, Abeer, Singh, Sonal, Atrooz, Fatin, Sadayappan, Sakthivel, McConnell, Bradley K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776749/
https://www.ncbi.nlm.nih.gov/pubmed/24058627
http://dx.doi.org/10.1371/journal.pone.0074784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776749/
https://www.ncbi.nlm.nih.gov/pubmed/24058627
http://dx.doi.org/10.1371/journal.pone.0074784

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