Simultaneous Activation of Kras and Inactivation of p53 Induces Soft Tissue Sarcoma and Bladder Urothelial Hyperplasia

The development of the Cre recombinase-controlled (Cre/LoxP) technique allows the manipulation of specific tumorigenic genes, temporarily and spatially. Our original intention of this study was to investigate the role of Kras and p53 in the development of urinary bladder cancer. First, to validate t...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoping, La Rosa, Francisco G., Genova, Elizabeth Erin, Huber, Kendra, Schaack, Jerome, DeGregori, James, Serkova, Natalie J., Li, Yuan, Su, Lih-Jen, Kessler, Elizabeth, Flaig, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776760/
https://www.ncbi.nlm.nih.gov/pubmed/24058630
http://dx.doi.org/10.1371/journal.pone.0074809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776760/
https://www.ncbi.nlm.nih.gov/pubmed/24058630
http://dx.doi.org/10.1371/journal.pone.0074809

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