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Sliding over the Blocks in Enzyme-Free RNA Copying – One-Pot Primer Extension in Ice

Template-directed polymerization of RNA in the absence of enzymes is the basis for an information transfer in the ‘RNA-world’ hypothesis and in novel nucleic acid based technology. Previous investigations established that only cytidine rich strands are efficient templates in bulk aqueous solutions w...

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Detalles Bibliográficos
Autores principales: Löffler, Philipp M. G., Groen, Joost, Dörr, Mark, Monnard, Pierre-Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776762/
https://www.ncbi.nlm.nih.gov/pubmed/24058695
http://dx.doi.org/10.1371/journal.pone.0075617