NSD1 Mitigates Caspase-1 Activation by Listeriolysin O in Macrophages

Mammals and plants share pathogen-sensing systems named nod-like receptors (NLRs). Some NLRs form the inflammasome, a protein scaffold that regulates the secretion of interleukin (IL)-1β and IL-18 by cleaving catalytically inactive substrates into mature cytokines. Here, we show an immune conservati...

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Detalles Bibliográficos
Autores principales: Sakhon, Olivia S., Victor, Kaitlin A., Choy, Anthony, Tsuchiya, Tokuji, Eulgem, Thomas, Pedra, Joao H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776765/
https://www.ncbi.nlm.nih.gov/pubmed/24058709
http://dx.doi.org/10.1371/journal.pone.0075911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776765/
https://www.ncbi.nlm.nih.gov/pubmed/24058709
http://dx.doi.org/10.1371/journal.pone.0075911

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